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pMineR TUTORIAL

July 9th, AIME 2024, Salt Lake City, USA

pMineR

R libraries for Process Mining for Healthcare

The pMineR project was born in 2016 and presented the first time at AIME 2016, in Vienna. We are glad for the opportunity to be here now to present the current state of this never-ending development, share visions and perspective and collects all the potential contributes of users and interested colleagues.

pMineR is an R library specifically designed to support Process Analysts to work in the clinical domain, providing Process Discovery algorithms, tools for Conformance Checking, Trace and Event Log analysis and methods for representing and working with given institutional processes, Consensus flow, Clinical Protocols, etc.. The library implements those features considering the most frequent statistical tools used in healthcare, such as non-parametric tests (Chi-Square, Fisher's Exact test), Surivival Analysis (Kaplan Meier curves, log-rank tests) and also Machine Learning methods and predictors to estimate the most relevant clinical outcomes in terms of events or times. It also implements an easy to use internal language for the interpretable representation of clinical guidelines and subsequent compliance analysis (crossing the domains of Process Mining in Healthcare and Clinical Computer Interpretable Guidelines)
For more info, visit : https://github.com/PMLiquidLab/pMineR.v046

The TUTORIAL

This Tutorial is designed to provide a general overwiew on pMineR, and introduce the partecipants to the main modules, by short hands-on sessions, to cope with Process Discovery, Conformance Checking and Statistical Analysis of paths, clinical guidelines, events and timing. The Tutorial will also exploit invited speakers to present their experience on real-world data analysis and open projects based on pMineR. Finally, an open round-table will be the opportunity to share opinions, ideas about the topic or a further evolution of the libraries. An indicative program is shonw below :

Frontal Lesson Modules ( 1h 30', Roberto Gatta ): Short lectures ( 1h ): Round Table ( 30' ):

pMineR/pMinShiny frontal lectures

50%

Real-world use cases, presented by invited speakers

30%

Round Table, interactive open discussion

20%

Tutorial Organizers

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Department of Information Engineering, Università degli Studi di Padova (IT) Department of Electrical, Computer and Biomedical Engineering at the University of Pavia (IT) Department of Industrial and Information Engineering, Università degli Studi di Pavia (IT) School of Computing and Engineering, University of Huddersfield (UK) Department of Oncology, Lausanne University Hospital, Lausanne (CH)

Program Committee

Stefania Orini
Dipartimento di Scienze Cliniche e Sperimentali, Università degli Studi di Brescia, Italy
Mariachiara Savino
Fondazione Policlinico Universitario A. Gemelli IRCCS, Real World Data Facility, Gemelli Generator
Massimiliano Filosto
Dipartimento di Scienze Cliniche e Sperimentali, Università degli Studi di Brescia, Italy
Federico Mastroleo
Department of Radiation Oncology, European Institute of Oncology (IEO) IRCCS, Milan, Italy; University of Piemonte Orientale, Novara, Italy.
Carlos Fernandes-Llatas
Universitat Politècnica de Valencia (Spain)

Tutorial Chair / in place Lecturer

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Department of Clinical and Experimental Sciences, Università degli Studi di Brescia (IT)



Supporting Associations

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The projects are now hosted on the gitHub area of the PMLiquidLab, a Liquid Lab (geographically distributed, cross-institutional and underground movment) lab of passionate researchers in the field of Process Mining for Healthcare. For more info, please visit: ( https://github.com/PMLiquidLab)

The initiative is kindly endorsed and sponsored by SIBIM, the Italian Scientific Society of Biomedical Informatics : https://www.sibim.it/

Selected References
  • Wicky A, Gatta R, Latifyan S, Micheli R, Gerard C, Pradervand S, Michielin O, Cuendet MA. Interactive process mining of cancer treatment sequences with melanoma real-world data. Front Oncol. 2023 Mar 21;13:1043683. doi: 10.3389/fonc.2023.1043683. PMID: 37025593; PMCID: PMC10072205.
  • Tavazzi E, Gatta R, Vallati M, Cotti Piccinelli S, Filosto M, Padovani A, Castellano M, Di Camillo B. Leveraging process mining for modeling progression trajectories in amyotrophic lateral sclerosis. BMC Med Inform Decis Mak. 2023 Feb 2;22(Suppl 6):346. doi: 10.1186/s12911-023-02113-7. PMID: 36732801; PMCID: PMC9896660.
  • Dagliati A, Gatta R, Malovini A, Tibollo V, Sacchi L, Cascini F, Chiovato L, Bellazzi R (2022). A Process Mining Pipeline to Characterize COVID-19 Patients' Trajectories and Identify Relevant Temporal Phenotypes From EHR Data. FRONTIERS IN PUBLIC HEALTH, vol. 10, ISSN: 2296-2565, doi: 10.3389/fpubh.2022.815674
  • Cuendet MA, Gatta R, Wicky A, Gerard CL, Dalla-Vale M, Tavazzi E, Michielin G, Delyon J, Ferahta N, Cesbron J, Lofek S, Huber A, Jankovic J, Demicheli R, Bouchaab H, Digklia A, Obeid M, Peters S, Eicher M, Pradervand S, Michielin O (2022). A differential process mining analysis of COVID-19 management for cancer patients. FRONTIERS IN ONCOLOGY, vol. 12, ISSN: 2234-943X, doi: 10.3389/fonc.2022.1043675
  • Placidi L, Boldrini L, Lenkowicz J, Manfrida S, Gatta R, Damiani A, Chiesa S, Ciellini F, Valentini V (2021). Process mining to optimize palliative patient flow in a high-volume radiotherapy department. TECHNICAL INNOVATIONS & PATIENT SUPPORT IN RADIATION ONCOLOGY, vol. 17, p. 32-39, ISSN: 2405-6324, doi: 10.1016/j.tipsro.2021.02.005
  • Tavazzi E, Gerard C L, Michielin O, Wicky A, Gatta R, Cuendet MA (2021). A Process Mining Approach to Statistical Analysis: Application to a Real-World Advanced Melanoma Dataset. In: Lecture Notes in Business Information Processing. LECTURE NOTES IN BUSINESS INFORMATION PROCESSING, vol. 406, p. 291-304, Springer Science and Business Media Deutschland GmbH, ISBN: 978-3-030-72692-8, ISSN: 1865-1348, 2020, doi: 10.1007/978-3-030-72693-5_22
  • Lenkowicz J, Gatta R, Masciocchi C, Casa C, Cellini F, Damiani A, Dinapoli N, Valentini V (2018). Assessing the conformity to clinical guidelines in oncology: An example for the multidisciplinary management of locally advanced colorectal cancer treatment. MANAGEMENT DECISION, vol. 56, p. 2172-2186, ISSN: 0025-1747, doi: 10.1108/MD-09-2017-0906
  • Gatta R, Vallati M, Lenkowicz J, Casa C, Cellini F, Damiani A, Valentini V (2018). A framework for event log generation and knowledge representation for process mining in healthcare. In: Proceedings - International Conference on Tools with Artificial Intelligence, ICTAI. PROCEEDINGS - INTERNATIONAL CONFERENCE ON TOOLS WITH ARTIFICIAL INTELLIGENCE, vol. 2018-, p. 647-654, IEEE Computer Society, ISBN: 978-1-5386-7449-9, ISSN: 1082-3409, grc, 2018, doi: 10.1109/ICTAI.2018.00103
  • Gatta R, Vallati M, Lenkowicz J, Rojas E, Damiani A, Sacchi L, De Bari B, Dagliati A, Fernandez-Llatas C, Montesi M, Marchetti A, Castellano M, Valentini V (2017). Generating and comparing knowledge graphs of medical processes using pMineR. In: Proceedings of the Knowledge Capture Conference, K-CAP 2017. p. 1-4, Association for Computing Machinery, Inc, ISBN: 9781450355537, usa, 2017, doi: 10.1145/3148011.3154464
  • Gatta R, Lenkowicz J, Vallati M, Rojas E, Damiani A, Sacchi L, De Bari B, Dagliati A, Fernandez-Llatas C, Montesi M, Marchetti A, Castellano M, Valentini V (2017). pMineR: An innovative R library for performing process mining in medicine. In: Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). LECTURE NOTES IN ARTIFICIAL INTELLIGENCE, vol. 10259, p. 351-355, Springer Verlag, ISBN: 978-3-319-59757-7, ISSN: 0302-9743, aut, 2017, doi: 10.1007/978-3-319-59758-4_42
CONTACT
Planet Earth
Email: roberto.gatta.bs@gmail.com

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